Ventolin Inhalers

- Pneumococcal Bacteremia with Pneumonia (9)

Pneumococcal Bacteremia with Pneumonia (9)Finally, in AIDS, there is partial or complete loss of both T cell-dependent and T cell-independent B-cell stimulation. Therefore, AIDS patients have lost most of their ability to direct an appropriate B-cell response to invading antigens (bacterial pathogens) and are much more prone to bacterial infections. This is despite the fact that there is a nonspecific polyclonal activation of B cells and often hypergammaglobulinemia, which may actually hinder a de novo antibody response. In ARC there is still some B cell-directed antibody response to antigen as well as residual protective antibody from previous antigen exposures.
The 100 percent survival rate in HIV-infected patients without AIDS who have pneumonia is probably related to a combination of a partially intact humoral immune system, young age, and relative lack of risk factors that predispose patients to an increased mortality. This survival rate is also consistent with a previous report of bacterial pneumonia among HIV-positive patients without AIDS. In this report, 14 of 144 HIV patients without AIDS developed a bacterial pneumonia and two patients (14.3 percent) died. The two patients who died had pneumonia due to Escherichia coli and Staphylococcus aureus, respectively.

July 16, 2013 Pulmonary function
Tags: aids patients antibiotic therapy hiv infection penicillin pneumonia septic shock