Ventolin Inhalers

- Pneumococcal Bacteremia with Pneumonia (11)

Pneumococcal Bacteremia with Pneumonia (11)Bacteremic pneumococcal pneumonia mortality in the AIDS population has a time frame similar to that in the non-HIV-infected patients. Six of eight patients died of septic shock. Five of six patients in septic shock also died within five days. Initial penicillin therapy was given to 37.5 percent of AIDS patients who died and 33 percent of patients who survived. Again, when mortality is evaluated only in patients who survived more than five days of antibiotic therapy, there were only three deaths (33.3 percent mortality). This is a reduced mortality that is still five times the mortality rate in patients without HIV infection.
The high mortality in the first five days of therapy is consistent with the observations of Austrian and Gold in 1964. They noted that 43 percent of all deaths from pneumococcal bacteremia occurred within 24 h of admission to the hospital. If deaths during this one-day period were eliminated {or excluded from data analysis), their mortality rate dropped to 12.2 percent. Their data also suggested that antimicrobial therapy had little or no effect on the outcome of infection among those destined, at the onset of illness, to die within five days. Septic shock at the onset of disease, as seen in our AIDS patients and those without HIV infection, was one of three major risk factors for death in another recent study of severe community-acquired pneumonia.

July 21, 2013 Pulmonary function
Tags: aids patients antibiotic therapy hiv infection penicillin pneumonia septic shock